Last time I sat down to make one of these, I was working on this game about forgetting someone you love. You'd stare at a washing machine and pick up some piece of clothing. When you did, you'd throw it into the machine, which would turn on. Each time it started spinning you'd see a nice-looking new scenario which you could look at with the first-person camera while you had a conversation with your loved one. Each of these memories would fade away before you could finish the conversation and you would go back to the washing machine, which would gradually deteriorate until it eventually fried up and exploded. That was when the game ended, so you could never wash all of the clothes, which kept piling up.
I think this was by far my best work, but no one ever got to play it, except for myself, because my HDD fried up before I could finish it. For some reason, I was not keeping backups or using any kind of source control, so I might have lost the whole thing. I never actually tried to repair the drive. I was so attached to that game that I decided I wouldn't make another one until I got over it.
I still keep the drive, just in case.